diff --git a/tests/opentelemetry-test-utils/test-requirements-constraints.txt b/tests/opentelemetry-test-utils/test-requirements-constraints.txt
new file mode 100644
index 000000000..5501c80e5
--- /dev/null
+++ b/tests/opentelemetry-test-utils/test-requirements-constraints.txt
@@ -0,0 +1,5 @@
+# these are required for weaver integration tests, we're running that only on linux / CPython
+# because of lack of support for gRPC on Windows in some cases.
+./opentelemetry-proto ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
+./exporter/opentelemetry-exporter-otlp-proto-common ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
+./exporter/opentelemetry-exporter-otlp-proto-grpc ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
diff --git a/tests/opentelemetry-test-utils/test-requirements.txt b/tests/opentelemetry-test-utils/test-requirements.txt
index 6b4dbcec0..7c066ea39 100644
--- a/tests/opentelemetry-test-utils/test-requirements.txt
+++ b/tests/opentelemetry-test-utils/test-requirements.txt
@@ -13,9 +13,6 @@ zipp==3.19.2
 -e opentelemetry-sdk
 -e opentelemetry-semantic-conventions
 -e tests/opentelemetry-test-utils
-# these are required for weaver integration tests, we're running that only on linux / CPython
-# because of lack of support for gRPC on Windows in some cases.
-# note: tox does not support PEP 508 markers on `-e` editable installs, so these are installed non-editable
-./opentelemetry-proto ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
-./exporter/opentelemetry-exporter-otlp-proto-common ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
-./exporter/opentelemetry-exporter-otlp-proto-grpc ; sys_platform != 'win32' and platform_python_implementation != 'PyPy'
+./opentelemetry-proto
+./exporter/opentelemetry-exporter-otlp-proto-common
+./exporter/opentelemetry-exporter-otlp-proto-grpc
diff --git a/tox.ini b/tox.ini
index d1c5aff8c..4fcbebba9 100644
--- a/tox.ini
+++ b/tox.ini
@@ -123,6 +123,7 @@ deps =
   semantic-conventions: -r {toxinidir}/opentelemetry-semantic-conventions/test-requirements.txt
 
   test-utils: -r {toxinidir}/tests/opentelemetry-test-utils/test-requirements.txt
+  test-utils: -c {toxinidir}/tests/opentelemetry-test-utils/test-requirements-constraints.txt
 
   opentelemetry-proto-gen-oldest: -r {toxinidir}/opentelemetry-proto/test-requirements.oldest.txt
   opentelemetry-proto-gen-latest: -r {toxinidir}/opentelemetry-proto/test-requirements.latest.txt

py310-test-opentelemetry-test-utils: install_deps> .tox/.tox/bin/uv pip install -r /home/rm/src/opentelemetry-python/tests/opentelemetry-test-utils/test-requirements.txt -c /home/rm/src/opentelemetry-python/tests/opentelemetry-test-utils/test-requirements-constraints.txt
error: Unnamed requirements are not allowed as constraints (found: `file:///home/rm/src/opentelemetry-python/opentelemetry-proto ; platform_python_implementation != 'PyPy' and sys_platform != 'win32'`)